Glass ionomer cement and composite resin - antibacterial effect
Midentistry review group

*Division of Public Oral Health, University of the Witwatersrand, Johannesburg, South Africa



Abstract
Glass-ionomers have a  higher inhibitory effect on bacterial growth than composite resin materials in vitro.

This abstract is prepared and maintained by Midentistry, currently published in The MI Compendium, 3rd edition, Copyright © 2009 Midentistry. The full data of this review is available in http://www.midentistry.com/secure-folder/content/3/mic11G1.asp   (ISBN: 0-620-34080-0)

This record should be cited as:  Midentistry. Glass ionomer cement and composite resin - antibacterial effect. Minim Interv Comp Database Syst Rev 2009; 2: RV01020091107.

This version first published online: August 12, 2009
Last revised: November 7, 2009



Objectives
To assess whether GIC have a better antibacterial effect than composite resin (with and without fluoride).


Search strategy
The trials were identified from a search of the PubMed database on: September 30, 2009 using the terms: "("Anti-Bacterial Agents"[Mesh] OR "Anti-Bacterial Agents "[Pharmacological Action]) AND ("Glass Ionomer Cements"[Mesh] OR "Cermet Cements"[Mesh]) AND  ("Composite Resins"[Mesh])


Inclusion criteria
All progressive 2-arm in-vitro, in-situ or in-vivo trials; with relevance to review question including computable data; published in English.

Exclusion criteria:
No computable continuous data for both, test- and control group; not all data from investigated units reported; no randomized or quasi-randomized study design for in-situ and in-vivo trials

Data collection and analysis
The systematic literature search found 129 trials of which 13 were identified to be in line with the inclusion criteria. Of these, 5 in-vitro trials were accepted for data extraction. From the reviewed trials 200 individual datasets were extracted and analyzed.

Main results
The results show that cured GIC appears to have an overall higher inhibitory effect on the bacterial growth of S. mutans, S. mitis, S.oralis and S. sanguis than composite resin materials with or without fluoride content. No difference was found between both material groups for Lactobacillus and S. sobrinus.

Authors' conclusions
The results from laboratory studies suggest that glass-ionomers have a  higher inhibitory effect on bacterial growth than composite resin materials. No in-situ or in-vitro trials could be identified to this review question and that limits the clinical applicability of the current results, which require confirmation in-situ and in-vivo.
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