Resin infiltration versus topical fluoride: carious lesion progression
Midentistry review group
*** Division of Public Oral Health, University of the Witwatersrand, Johannesburg, South Africa
Abstract
There is less lesion progress after resin infiltration.
This abstract is prepared and maintained by Midentistry, currently published in The MI Compendium, 3rd edition, Copyright © 2009, 2010 Midentistry. The full data of this review is available in http://www.midentistry.com/secure-folder/content/3/fur0501.asp (ISBN: 0-620-34080-0)
This record should be cited as: Midentistry. Resin infiltration versus topical fluoride: carious lesion progression. Minim Interv Comp Database Syst Rev 2010; 1: RV00720103003
This version first published online: March 30, 2010
Last revised: March 30, 2010
Objectives
To assess whether resin infiltration technique is more effective to stop progression of caries lesions than remineralisation therapy.
Search strategy
The trials were identified from a search of the PubMed database on: March 27, 2010 using the terms: "resin infiltration OR caries infiltration" plus grey literature search in Google using same search terms.
Inclusion criteria
1. Relevant to review question / outcome measure: stop of caries progression on human tissue
2. Published in English or German language
3. Clinical randomized or quasi randomized control trial (RCT, quasi-RCT)
Data collection and analysis
The systematic literature search identified one splitmouth (quasi-RCT) containing 2 datasets in which the treatment effect of resin infiltration therapy was compared to topical fluoride application after 1 year. Quality assessment of the trial gave following results:
(1) Generation of randomized sequence (allocation) = A (adequate)
(2) Allocation concealment = B (unclear)
(3) Blind outcome assessment reported = A (yes)
(4) Completeness of follow up (clear explanation for withdrawals and loss-to-follow-up in each treatment group) = A (yes, drop out less than 30%)
Data extraction from the trial resulted in 2 separate datasets:
DS01- Clinical assessed lesion progression after 1 year;
DS02- radiographic assessed lesion progression after 1 year.
Main results and Authors' conclusions
The established relative risks (RR) indicated that resin infiltration reduced the chance of lesion progression after 1 year by 60% (clinical assessment) / 62% (radiographically assessment) than if the lesions would have been treated with topical fluoride. However, possibility of selection bias influence/overestimation of results may exist due to unclear concealment of the random allocation (B). The results of the single trial indicate that resin infiltration technique may be more effective in the prevention of progression of carious lesion than topical fluoride application after 1 year. Further high quality trials are needed in order to confirm these initial findings.
